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Application Effect of Tengli Jujube lung purging Decoctionin Cough and Asthma Treatment Based on Network Pharmacology

Xiaoxi Liu, Wei Meng

Abstract


In today’s society, the incidence of respiratory diseases such as cough and asthma is on the rise, presenting numerous clinical challenges in their treatment. This study employs network pharmacology to investigate the therapeutic effects of the traditional Chinese medicine compound, Tengli Dazao Xiefei Decoction, on respiratory diseases. We collected and integrated data on the active components and their corresponding pharmacological targets in Tengli Dazao Xiefei Decoction, and used bioinformatics techniques to analyze the potential mechanisms by which Tengli Dazao Xiefei Decoction treats cough and asthma. The study found that Tengli Dazao Xiefei Decoction effectively inhibits inflammatory responses, reduces mucus blockage, and stabilizes breathing by interacting with several key biological pathways and targets. Clinical observations also demonstrated that this formula significantly improves cough and asthma, with notable effects and no significant side effects, making it worthy of widespread clinical application. This study may provide new insights and references for the development of respiratory disease medications and the optimization of traditional Chinese medical treatments in clinical settings.

Keywords


Network pharmacology; Bupleurum and jujube lung purgative decoction; Respiratory tract diseases; Inflammatory response; Clinical efff cacy

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References


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DOI: http://dx.doi.org/10.18686/ahe.v9i3.14156

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