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High Flow Nasal Catheter (HFNC) for Sepsis Induced Respiratory Failure after Extubation Meta Analysis of Clinical Control Studies on Reintubation Rate and Mortality

Bo Li, Xuanguo Zhang, Gaojie Wang, Qiuzhen Yuan, Minjuan Shi, Li Xi

Abstract


Objective: To analyze the reintubation rate and mortality of patients with sepsis complicated (or induced) respiratory failure after extubation, and to seek evidence-based basis for the efficacy of HFNC in the re intubation rate and mortality of sepsis induced respiratory failure after extubation.
Methods: The databases of PubMed, EMBASE, Ovid, CNKI, CBM, VIP and Wanfang were searched to find the clinical studies of patients with sepsis and respiratory failure, and meta-analysis was carried out by Stata software.
Results: Meta analysis showed that there was no significant difference between HFNC and noninvasive positive pressure ventilation (NPPV) in 72 hour reintubation rate, mortality during ICU and 28-day in hospital.
Conclusion: The reintubation rate and mortality of HFNC after extubation in sepsis induced respiratory failure are equivalent to that of NPPV.

Keywords


Sepsis; Respiratory failure; High flow nasal catheter; Noninvasive positive pressure ventilation

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References


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DOI: http://dx.doi.org/10.18686/ahe.v7i2.7116

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